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Efficient Methodology for Selective Alkylation of Hydrazine Derivatives

Aleksei Bredihhin, Ulrich M. Groth and Uno Mäeorg*

*Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia, Email: unochem.ut.ee

A. Bredihhin, U. M. Groth, U. Mäeorg, Org. Lett., 2007, 9, 1097-1099.

DOI: 10.1021/ol070026w


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Abstract

Formation and use of a nitrogen dianion for selective hydrazine alkylation provides a fast and easy access to substituted hydrazines, which are widely used as drugs, pesticides, and precursors for a variety of compounds in organic synthesis.

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Use of Polyanions for Alkylation of Hydrazine Derivatives

A. Bredihhin, U. Mäeorg, Org. Lett., 2007, 9, 4975-4977.


Key Words

Hydrazines


ID: J54-Y2007-0940