Organic Chemistry Portal



Efficient Methodology for Selective Alkylation of Hydrazine Derivatives

Aleksei Bredihhin, Ulrich M. Groth and Uno Mäeorg*

*Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia, Email:

A. Bredihhin, U. M. Groth, U. Mäeorg, Org. Lett., 2007, 9, 1097-1099.

DOI: 10.1021/ol070026w (free Supporting Information)

see article for more reactions


Formation and use of a nitrogen dianion for selective hydrazine alkylation provides a fast and easy access to substituted hydrazines, which are widely used as drugs, pesticides, and precursors for a variety of compounds in organic synthesis.

see article for more examples

Use of Polyanions for Alkylation of Hydrazine Derivatives

A. Bredihhin, U. Mäeorg, Org. Lett., 2007, 9, 4975-4977.

Key Words


ID: J54-Y2007-0940