Organic Chemistry Portal

Abstracts

Search:

A New Versatile Synthesis of Esters from Grignard Reagents and Chloroformates

Daniela Bottalico, Vito Fiandanese, Giuseppe Marchese, Angela Punzi*

*Dipartimento di Chimica, UniversitÓ di Bari, Via Orabona 4, 70126 Bari, Italy, Email: punzichimica.uniba.it

D. Bottalico, V. Fiandanese, G. Marchese, A. Punzi, Synlett, 2007, 974-976.

DOI: 10.1055/s-2007-973861


Abstract

An efficient cross-coupling reaction of chloroformates with organocopper reagents, derived from Grignard reagents, cuprous bromide and lithium bromide, provides esters in good yields.

see article for more examples



Key Words

organometallic reagents, cross-coupling, chemoselectivity, esters


ID: J60-Y2007-1040