A New Versatile Synthesis of Esters from Grignard Reagents and Chloroformates
Daniela Bottalico, Vito Fiandanese, Giuseppe Marchese, Angela Punzi*
*Dipartimento di Chimica, Università di Bari, Via Orabona 4, 70126 Bari,
Italy, Email: punzi
chimica.uniba.it
D. Bottalico, V. Fiandanese, G. Marchese, A. Punzi, Synlett, 2007, 974-976.
DOI: 10.1055/s-2007-973861
Abstract
An efficient cross-coupling reaction of chloroformates with organocopper reagents, derived from Grignard reagents, cuprous bromide and lithium bromide, provides esters in good yields.
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Key Words
organometallic reagents, cross-coupling, chemoselectivity, esters
ID: J60-Y2007-1040
