Synthesis and Characterization of R₂PN=P(ⁱBuNCH₂CH₂)₃N: A New Bulky Electron-Rich Phosphine for Efficient Pd-Assisted Suzuki-Miyaura Cross-Coupling Reactions

Jesudoss V. Kingston and John G. Verkade*

*Department of Chemistry, Iowa State University, Ames, Iowa 50011, Email: jverkadeiastate.edu

J. V. Kingston, J. G. Verkade, J. Org. Chem., 2007, 72, 2816-2822.

DOI: 10.1021/jo062452l

---

Abstract

A catalyst system of sterically bulky electron-rich phosphines and Pd(OAc)₂ was particularly efficient for the coupling of arylboronic acids with aryl bromides as well as aryl chlorides to give biaryls in excellent yields.

see article for more examples

---

---

Key Words

Suzuki Coupling, Biaryls

---

ID: J42-Y2007-1090