An Efficient Method for the α-Acetoxylation of Ketones
Jinmei Sheng, Xiaolong Li, Mingfang Tang, Botao Gao, Guosheng Huang*
*State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
Lanzhou 730000, P. R. of China, Email: hgs2368
163.com
J. Sheng, Y. Li, M. Tang, B. Gao, G. Huang, Synthesis, 2007, 1165-1168.
DOI: 10.1055/s-2007-965984
Abstract
α-Acetoxylation of ketones catalyzed by iodobenzene using acetic anhydride and 30% aqueous hydrogen peroxide as the oxidant is an effective and economical method for the preparation of α-acetoxy ketones in good yields.
see article for more examples
An Efficient Method for the Synthesis of α-Hydroxyalkyl Aryl Ketones
C. Chen, X. Feng, G. Zhang, Q. Zhao, G. Huang, Synthesis, 2008, 3205-3208.
Key Words
acetoxylation, iodobenzene, α-acetoxy ketones, iodine(III) catalysts, oxidation, hydrogen peroxide
ID: J66-Y2007-1140
