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An Efficient Method for the α-Acetoxylation of Ketones

Jinmei Sheng, Xiaolong Li, Mingfang Tang, Botao Gao, Guosheng Huang*

*State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China, Email:

J. Sheng, Y. Li, M. Tang, B. Gao, G. Huang, Synthesis, 2007, 1165-1168.

DOI: 10.1055/s-2007-965984


α-Acetoxylation of ketones catalyzed by iodobenzene using acetic anhydride and 30% aqueous hydrogen peroxide as the oxidant is an effective and economical method for the preparation of α-acetoxy ketones in good yields.

see article for more examples

An Efficient Method for the Synthesis of α-Hydroxyalkyl Aryl Ketones

C. Chen, X. Feng, G. Zhang, Q. Zhao, G. Huang, Synthesis, 2008, 3205-3208.

Key Words

acetoxylation, iodobenzene, α-acetoxy ketones, iodine(III) catalysts, oxidation, hydrogen peroxide

ID: J66-Y2007-1140