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Rhodium-Catalyzed Intramolecular C-H Insertion of α-Aryl-α-diazo Ketones

Douglass F. Taber* and Weiwei Tian

*Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, Email:

D. F. Taber, W. Tian, J. Org. Chem., 2007, 72, 3207-3210.

DOI: 10.1021/jo0624694 (free Supporting Information)

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α-Aryl-α-diazo ketones derived from direct diazo transfer with α-aryl ketones cyclize efficiently in the presence of Rh catalysts to give the corresponding α-aryl cyclopentanones.

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Key Words

Diazoketones, Cyclopentanones

ID: J42-Y2007-1240