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Bioactive 2-Oxazolines: A New Approach via One-Pot, Four-Component Reaction

Lijun Fan, Emil Lobkovsky and Bruce Ganem*

*Department of Chemistry & Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853-1301, Email:

L. Fan, E. Lobkovsky, B. Ganem, Org. Lett., 2007, 9, 2015-2017.

DOI: 10.1021/ol070694h (free Supporting Information)


Substituted 2-oxazolines, that are found in several families of bioactive natural products, can be prepared in an efficient and general one-pot, four-component condensation.

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Key Words

2-Oxazolines, Multicomponent Reactions

ID: J54-Y2007-1560