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Preparation of Amidines by Amidoxime Reduction with Potassium Formate

Kristina Nadrah, Marija Sollner Dolenc*

*Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia, Email:

K. Nadrah, M. Sollner Dolenc, Synlett, 2007, 1257-1258.

DOI: 10.1055/s-2007-977444


Amidines can be prepared by reducing acylated amidoximes with potassium formate. This method has proved to be very simple and effective.

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Key Words

palladium, reductions, amidines, green chemistry, formic acid

ID: J60-Y2007-1580