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Palladium-Catalyzed Reduction of N-(tert-Butoxycarbonyl)indoles by Polymethylhydrosiloxane

Srivari Chandrasekhar*, Debjit Basu, Ch. Raji Reddy

*Organic Division I, Indian Institute of Chemical Technology, Hyderabad 500007, India, Email:

S. Chandrasekhar, D. Basu, C. R. Reddy, Synthesis, 2007, 1509-1512.

DOI: 10.1055/s-2007-966029


An efficient, palladium-catalyzed reduction of N-(tert-butoxycarbonyl)indoles gives N-(tert-butoxy­carbonyl)indolines in good yields in the presence of polymethylhydrosiloxane (PMHS) as reducing agent at room temperature.

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Key Words

palladium catalysis, reduction, indoles, indolines, polymethylhydrosiloxane

ID: J66-Y2007-1640