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Direct Pd-Catalyzed Arylation of 1,2,3-Triazoles

Stepan Chuprakov, Natalia Chernyak, Alexander S. Dudnik and Vladimir Gevorgyan*

*Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607-7061, Email:

S. Chuprakov, N. Chernyak, A. S. Dudnik, V. Gevorgyan, Org. Lett., 2007, 9, 2333-2336.

DOI: 10.1021/ol070697u


A highly efficient method for the synthesis of multisubstituted 1,2,3-triazoles via a direct Pd-catalyzed C-5 arylation has been developed.

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Key Words

1,2,3-Triazoles, Arylation

ID: J54-Y2007-1870