Palladium-Catalyzed Cross-Coupling Reactions of Substituted Aryl(dimethyl)silanols
Scott E. Denmark*, Michael H. Ober
*Roger Adams Laboratory, Department of Chemistry University of Illinois, Urbana, Illinois 61801, Email: denmarkscs.uiuc.edu
S. E. Denmark, M. H. Ober, Adv. Synth. Catal., 2004, 346, 1703-1715.
Cesium carbonate and cesium hydroxide monohydrate are effective activators for the palladium-catalyzed cross coupling of electron-rich aryl(dimethyl)silanols with aryl iodides and aryl bromides. Extensive optimization led to the identification of key variables such as solvent, catalyst, and hydration level.
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Cross-Coupling Reactions of Aromatic and Heteroaromatic Silanolates with Aromatic and Heteroaromatic Halides
S. E. Denmark, R. C. Smith, W.-T. T. Chang, J. M. Muhuhi, J. Am. Chem. Soc., 2008, 131, 3104-3118.
Hiyama-Denmark Coupling, biaryls, C-C bond formation, cesium carbonate, cesium hydroxide, fluoride-free, hydration effect