A Catalytic Method for the Reduction of Secondary and Tertiary Phosphine Oxides
Mikaël Berthod, Alain Favre-Réguillon, Jahjah Mohamad, Gérard Mignani, Gordon Docherty, Marc Lemaire*
*Laboratoire de Catalyse et Synthèse Organique, Institut de
Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), CNRS, UMR5246,
Université Lyon 1, 43 Boulevard du 11 Novembre 1918, 69622 Villeurbanne, France, Email:
marc.lemaire
univ-lyon1.fr
M. Berthod, A. Favre-Réguillon, J. Mohamad, G. Mignani, G. Docherty, M. Lemaire, Synlett, 2007, 1545-1548.
DOI: 10.1055/s-2007-982536
Abstract
TMDS is an efficient hydride source for the reduction of tertiary and secondary phosphine oxides using a catalytic amount of Ti(OiPr)4. All classes of tertiary phosphine oxides, such as triaryl, trialkyl, and diphosphine were effectively reduced.
see article for more examples
Key Words
phosphorus, reduction of phosphine oxides, titanium, hydrosiloxane, tetramethyldisiloxane, phosphine oxides
ID: J60-Y2007-1960
