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Preparation of Polyfunctional Acyl Azides

Alan R. Katritzky,* Khalid Widyan and Kostyantyn Kirichenko

*Center of Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, Email:

A. R. Katritzky, K. Widyan, K. Kirichenko, J. Org. Chem., 2007, 72, 5802-5804.

DOI: 10.1021/jo070162e


A general synthesis of acyl azides from the corresponding N-acyl benzotriazoles affords acyl azides in good yields and avoids the use of acid activators and NO+ equivalents typically employed to synthesize these compounds from acid chlorides and hydrazides, respectively.

see article for more examples

Efficient Conversion of Carboxylic Acids into N-Acylbenzotriazoles

A. R. Katritzky, N. Kirichenko, B. V. Rogovoy, Synthesis, 2003, 2777-2780.

Key Words

acyl azides

ID: J42-Y2007-2330