Bromination of Deactivated Aromatics: A Simple and Efficient Method
K. Rajesh, M. Somasundaram, R. Saiganesh* and K. K. Balasubramanian
*Shasun Research Centre, No. 27, Vandaloor-Kelambakkam Road,
Keelakottaiyur, Chennai-600 048, India, Email: saiganesh
shasun.com
K. Rajesh, M. Somasundaram, R. Saiganesh, K. K. Balasubramanian, J. Org. Chem., 2007, 72, 5867-5869.
DOI: 10.1021/jo070477u
Abstract
Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated sulfuric acid. Mild reaction conditions and simple workup provides a practical and commercially viable route for the synthesis of bromo compounds of deactivated aromatics in good yields.
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ID: J42-Y2007-2360
