A Catalytic Synthesis of Aziridines without the Usual Byproducts
Arindam Mazumdar, Zheng Xue, Michael F. Mayer*
*Department of Chemistry and Biochemistry, Texas Tech
University, Lubbock, TX 79409-1061, USA, Email: mf.mayer
ttu.edu
A. Mazumdar, Z. Xue, M. F. Mayer, Synlett, 2007, 2025-2028.
Abstract
Complementary to existing routes, Lewis acid catalyzed reactions of phenyldiazomethane with α-imino esters selectively produce cis-aziridine-2-carboxylates without competitive formation of enamino ester or carbene dimer byproducts.
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Key Words
catalysis, aziridines, diazo compounds, heterocycles, imines, Lewis acids
ID: J60-Y2007-2560
