Organic Chemistry Portal



Ni(II)-(σ-Aryl) Complex: A Facile, Efficient Catalyst for Nickel-Catalyzed Carbon−Nitrogen Coupling Reactions

Chen Chen and Lian-Ming Yang*

*Beijing National Laboratory For Molecular Sciences (BNLMS), Laboratory of New Materials, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China, Email:

C. Chen, L-M. Yang, J. Org. Chem., 2007, 72, 6324-6327.

DOI: 10.1021/jo0709448

see article for more reactions


Air- and moisture-stable Ni(II)-(σ-aryl) complexes, associated with N-heterocyclic carbene ligands, produce a catalytically active Ni(0) species in situ for an efficient amination of aryl chlorides with anilines and secondary cyclic amines under mild conditions.

see article for more examples

Arylation of Diarylamines Catalyzed by Ni(II)-PPh3 System

C. Chen, L.-M. Yang, Org. Lett., 2005, 7, 2209-2211.

Key Words

Amination, Arylamines

ID: J42-Y2007-2630