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The Effect of Iodine on the Peroxidation of Carbonyl Compounds

Katja Žmitek, Marko Zupan, Stojan Stavber and Jernej Iskra*

*Laboratory of Organic and Bioorganic Chemistry, “Jožef Stefan” Institute, Jamova 39, Ljubljana, Slovenia, Email:

K. Žmitek, M. Zupan, S. Stavber, J. Iskra, J. Org. Chem., 2007, 72, 6534-6540.

DOI: 10.1021/jo0708745

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Ketones reacted with hydrogen peroxide in the presence of iodine to yield gem-dihydroperoxides in acetonitrile and hydroperoxyketals in methanol in good yields. Aromatic aldehydes were also converted to gem-dihydroperoxides in acetonitrile and to hydroperoxyacetals in methanol.

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Key Words

peroxides, hydrogen peroxide

ID: J42-Y2007-2680