Diastereoselective Synthesis of 1-Aryl-2-Amino-Cyclopropane Carboxylates
Trude Melby, Rachael Anne Hughes, Tore Hansen*
*Department of Chemistry, University of Oslo, Sem Sælands vei 26, 0315 Oslo, Norway, Email: torehanskjemi.uio.no
T. Melby, R. A. Hughes, T. Hansen, Synlett, 2007, 2277-2279.
Methyl 1-aryl-2-amino-cyclopropane carboxylates have been readily synthesized in high yields by Rh-catalyzed decomposition of aryldiazoacetates in the presence of N-vinylphthalimide. The reaction is highly trans-selective.
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