Cobalt-Catalyzed Reductive Coupling of Activated Alkenes with Alkynes
Hong-Tai Chang, Thiruvellore Thatai Jayanth, Chun-Chih Wang and Chien-Hong Cheng*
*Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan, Email: chchengmx.nthu.edu.tw
H.-T. Chang, T. T. Jayanth, C.-C. Wang, C.-H. Cheng, J. Am. Chem. Soc., 2007, 129, 12032-12041.
DOI: 10.1021/ja073604c (free Supporting Information)
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Cobalt complex/Zn systems effectively catalyze the reductive coupling of activated alkenes with alkynes in the presence of water to give substituted alkenes with very high regio- and stereoselectivity in excellent yields.
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