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Anion-Functionalized Ionic Liquids Enhance the CuI-Catalyzed Cross-Coupling Reaction of Sulfinic Acid Salts with Aryl Halides and Vinyl Bromides

Ming Bian, Fada Xu, Cheng Ma*

*Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China, Email:

M. Bian, F. Xu, C. Ma, Synthesis, 2007, 2951-2956.

DOI: 10.1055/s-2007-990778


An easily accessible, anion-functionalized ionic liquid, 1-ethyl-3-methylimidazolium (S)-2-amino-3-methylbutyric acid salt, [emim][Val], is an efficient additive for the CuI-catalyzed coupling reaction of sulfinic acid salts with aryl iodides, aryl bromides and vinyl bromides, leading to sulfones in good yields.

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Key Words

ionic liquids, homogeneous catalysis, cross-coupling, copper, sulfones

ID: J66-Y2007-3200