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A New Modification of the Bohlmann-Rahtz Pyridine Synthesis

Mark C. Bagley*, James W. Dale, Justin Bower

*Department of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK, Email: bagleymccf.ac.uk

M. C. Bagley, J. W. Dale, J. Bower, Synlett, 2001, 1149-1151.

DOI: 10.1055/s-2001-15140


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Abstract

A range of highly functionalised pyridines is prepared from enamino and alkynones in a single synthetic step by the use of acetic acid or amberlyst 15 ion exchange resin at 50°C.

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A new mild method for the one-pot synthesis of pyridines

X. Xiong, M. C. Bagley, K. Chapaneri, Tetrahedron Lett., 2004, 45, 6121-6124.

A new one-step synthesis of pyridines under microwave-assisted conditions

M. C. Bagley, R. Lunn, X. Xiong, Tetrahedron Lett., 2002, 43, 8331-8334.


Key Words

pyridines, cyclisations, heterocycles, Michael Additions, Bohlmann-Rahtz Pyridine Synthesis


ID: J60-Y2001-670