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A Facile, One-Pot Procedure for Forming Diarylimines from Nitroarenes and Benzaldehydes

Andrew L. Korich, Thomas S. Hughes*

*Chemistry Department, Cook Physical Science Building, University of Vermont, 82 University Place, Burlington, VT 05405, USA, Email:

A. L. Korich, T. S. Hughes, Synlett, 2007, 2602-2604.

DOI: 10.1055/s-2007-986668


An intermolecular reductive Schiff base formation from nitroarenes and benzaldehydes to yield diarylimines is carried out in the presence of iron powder and dilute acid. This process tolerates various functional groups and often proceeds quantitatively with no need for purification.

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Key Words

reduction of nitro compounds, condensation, imines, Schiff bases, iron, green chemistry

ID: J60-Y2007-3350