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Efficient Carbonylation Reactions in Phosphonium Salt Ionic Liquids: Anionic Effects

James McNulty,* Jerald J. Nair and Al Robertson

*Department of Chemistry, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4M1, Canada, Email:

J. McNulty, J. J. Nair, A. Robertson, A. Lei, Org. Lett., 2007, 9, 4575-4578.

DOI: 10.1021/ol702081g


Phosphonium bromide ionic liquids are superior media in the carbonylation of aryl and vinyl halides. Formation of acid bromide intermediates was detected in control experiments providing an extended view on the overall catalytic cycle involved. Solvent-free product isolation and recycling of the ionic liquid containing active Pd-catalyst are also demonstrated.

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Key Words

Benzoates, Aminocarbonylation, Ionic Liquids, Multicomponent Reactions

ID: J54-Y2007-3430