Aminocarbonylation of Aryl Halides Using a Nickel Phosphite Catalytic System
Jinhun Ju, Miso Jeong, Jeongju Moon, Hyun Min Jung and Sunwoo Lee*
*Department of Chemistry, Chonnam National University, 300 Yongbong-dong, Buk-gu, Gwangju 500-757, Republic of Korea, Email: sunwoochonnam.ac.kr
J. Ju, M. Jeong, J. Moon, H. M. Jung, S. Lee, Org. Lett., 2007, 9, 4615-4618.
DOI: 10.1021/ol702058e (free Supporting Information)
Nickel catalysis enables a very efficient aminocarbonylation reaction to be performed between aryl iodides or bromides and N,N-dimethylformamide (DMF) in the presence of sodium methoxide and a phosphite ligand, which is very stable to air and moisture and, furthermore, inexpensive.
see article for more examples