Pd(quinoline-8-carboxylate)₂ as a Low-Priced, Phosphine-Free Catalyst for Heck and Suzuki Reactions

Xin Cui, Juan Li, Zhi-Ping Zhang, Yao Fu, Lei Liu* and Qing-Xiang Guo*

*Department of Chemistry, University of Science and Technology of China, Hefei 230026, P. R. of China, Email: leiliuustc.edu.cn, qxguoustc.edu.cn

X. Cui, J. Li, Z.-P. Zhang, Y. Fu, L. Liu, Q.-X. Guo, J. Org. Chem., 2007, 72, 9342-9345.

DOI: 10.1021/jo701783k

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Abstract

N,O-Bidentate compounds were systematically evaluated as phosphine-free ligands for Pd-catalyzed C-C bond-formation reactions. Pd(quinoline-8-carboxylate)₂ was identified as a very efficient, and low-priced, phosphine-free catalyst for Heck as well as Suzuki reactions of unactivated aryl bromides.

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N,N-Dimethyl-β-alanine as an Inexpensive and Efficient Ligand for Palladium-Catalyzed Heck Reaction

X. Cui, Z. Li, C.-Z. Tao, Y. Xu, J. Li, L. Liu, Q.-X. Guo, Org. Lett., 2006, 8, 2467-2470.

Pd(N,N-Dimethyl β-alaninate)₂ as a High-Turnover-Number, Phosphine-Free Catalyst for the Suzuki Reaction

X. Cui, T. Qin, J.-R. Wang, L. Liu, Q.-X. Guo, Synthesis, 2007, 393-399.

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Key Words

Heck Reaction

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ID: J42-Y2007-3700