A Simple and Efficient Procedure of Low Valent Iron- or Copper-Mediated Reformatsky Reaction of Aldehydes
Angshuman Chattopadhyay* and Akhil Kr. Dubey
*Bio-Organic Division, Bhabha Atomic Research Centre,
Mumbai-400 085, India,
Email: achat
apsara.barc.ernet.in
A. Chattopadhyay, A. Kr. Dubey, J. Org. Chem., 2007, 72, 9357-9359.
DOI: 10.1021/jo0710984
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Abstract
An operationally simple and very efficient Reformatsky reaction of aldehydes has been carried out in THF in the presence of low valent iron or copper which were prepared in situ employing a bimetal redox strategy through reduction of Fe(III) or Cu(II) salts with magnesium.
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Key Words
Reformatsky Reaction, magnesium, low valent iron
ID: J42-Y2007-3730
