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Highly selective silver(I) oxide mediated monoprotection of symmetrical diols

Abderrahim Bouzide* and Gilles Sauvé

*Institut Armand-Frappier, Université du Québec, 531 boul. des Prairies, Laval, Québec, Canada, H7N 4Z3

A. Bouzide, G. Sauvé, Tetrahedron Lett., 1997, 38, 5945-5948.

DOI: 10.1016/S0040-4039(97)01328-2

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Treatment of a symmetrical diol with Ag2O and an alkyl halide gave the monoprotected derivative in very good yield.

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Key Words

benzyl ethers

ID: J72-Y1997-670