Cobalt-Catalyzed Synthesis of Tertiary Azides from α,α-Disubstituted Olefins under Mild Conditions Using Commercially Available Reagents
Boris Gaspar, Jérôme Waser, Erick M. Carreira*
*Laboratorium für Organische Chemie, ETH Hönggerberg, HCI
G336, 8093 Zürich, Switzerland,
Email: carreira
org.chem.ethz.ch
B. Gaspar, J. Waser, E. M. Carreira, Synthesis, 2007, 3839-3845.
Abstract
A cobalt-catalyzed hydroazidation of α,α-disubstituted olefins with commercially available azide sources provides tertiary azides in useful yields and tolerates a variety of functional groups.
see article for more examples
Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides
J. Waser, H. Nambu, E. M. Carreira, J. Am. Chem. Soc., 2005, 127, 8294-8295.
Key Words
alkenes, hydroazidation, homogeneous catalysis, cobalt, alkyl azides tetramethyldisiloxane (TMDSO)
ID: J66-Y2007-4130
