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A Facile Synthesis of 1-Arenesulfonylazetidines through Reaction of 1-Arenesulfonylaziridines with Dimethylsulfoxonium Methylide Generated under Microwave Irradiation

Sarika Malik*, Upender K. Nadir

*Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110 016, India, Email:

S. Malik, U. K. Nadir, Synlett, 2008, 108-110.

DOI: 10.1055/s-2007-1000838


A simple, efficient and general method has been developed for the synthesis of 1-arenesulfonylazetidines through a one-pot reaction of 1-arenesulfonylaziridines with dimethylsulfoxonium methylide, generated under microwave irradiation, using alumina as solid support.

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Key Words

azo compounds, aziridines, azetidines, ring expansion, sulfur, ylides, heterocycles

ID: J60-Y2008-0110