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An improved 1,3-diene synthesis from alkyne and ethylene using cross-enyne metathesis

Keisuke Tonogakia and Miwako Mori

*Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan, Email:

K. Tonogakia, M. Mori, Tetrahedron Lett., 2002, 43, 2235-2238.

DOI: 10.1016/S0040-4039(02)00215-0


Synthesis of 1,3-diene from alkyne and ethylene (1 atm) was improved using a ruthenium NHC carbene complex having a heterocyclic carbene as a ligand. Various 1,3-dienes could be synthesized from alkynes and ethylene.

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Key Words

Enyne Metathesis, 1,3-Dienes

ID: J72-Y2002-1800