Rhodium Fluorapatite Catalyst for the Synthesis of Trisubstituted Olefins via Cross Coupling of Baylis-Hillman Adducts and Arylboronic Acids
M. Lakshmi Kantam,* K. B. Shiva Kumar and B. Sreedhar
*Inorganic and Physical Chemistry Division, Indian Institute
of Chemical Technology, Hyderabad 500 007, India, Email: mlakshmi
iict.res.in
M. L. Kantam, K. B. S. Kumar, B. Sreedhar, J. Org. Chem., 2008, 73, 320-322.
DOI: 10.1021/jo701982m
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Abstract
Treatment of fluorapatite with an aqueous solution of RhCl3 resulted in rhodium-exchanged fluorapatite catalyst (RhFAP), which successfully promoted cross coupling of Baylis-Hillman adducts with a variety of arylboronic acids to yield trisubstituted olefins in a highly stereoselective manner. RhFAP was recovered quantitatively by simple filtration and reused with almost consistent activity.
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Key Words
Allylation, Baylis-Hillman Adducts
ID: J42-Y2008-0250
