An Efficient, One-Pot Synthesis of S-Alkyl Thiocarbamates from the Corresponding Thiols Using the Mitsunobu Reagent
Devdutt Chaturvedi*, Nisha Mishra, Virendra Mishra
*Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India, Email: ddchaturvedi002yahoo.co.in
D. Chaturvedi, N. Mishra, V. Mishra, Synthesis, 2008, 355-357.
A mild and efficient Mitsunobu-based protocol has been developed for the synthesis of various S-alkyl thiocarbamates from the corresponding thiols and amines using gaseous carbon dioxide, in good to excellent yields.
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