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Heterogeneous Copper Catalyst for the Cycloaddition of Azides and Alkynes without Additives under Ambient Conditions

In Soo Park, Min Serk Kwon, Youngkwon Kim, Jae Sung Lee and Jaiwook Park*

*Department of Chemistry and Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), San 31 Hyojadong, Pohang, Kyeongbuk 790-784, Republic of Korea, Email:

I. S. Park, M. S. Kwon, Y. Kim, J. S. Lee, J. Park, Org. Lett., 2008, 10, 497-500.

DOI: 10.1021/ol702790w (free Supporting Information)


Immobilized copper nanoparticles in aluminum oxyhydoxide fiber showed high catalytic activity for the cycloaddition of various alkynes to azides at room temperature. The catalyst can be recycled up to five times without significant loss of activity.

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Key Words

1,2,3-Triazoles, Click Chemistry

ID: J54-Y2008-0360