Nickel-Catalyzed Asymmetric Negishi Cross-Couplings of Secondary Allylic Chlorides with Alkylzincs
Sunghee Son and Gregory C. Fu*
*Department of Chemistry, Massachusetts Institute of
Technology, Cambridge, Massachusetts 02139, Email: gcf
mit.edu
S. Son, G. C. Fu, J. Am. Chem. Soc., 2008, 130, 2756-2757.
DOI: 10.1021/ja800103z
Abstract
An effective nickel/Pybox catalyst for regioselective asymmetric Negishi cross-couplings of racemic secondary allylic chlorides with readily available organozinc halides has been developed.
see article for more examples
Nickel-Catalyzed Asymmetric Cross-Couplings of Racemic Propargylic Halides with Arylzinc Reagents
S. W. Smith, G. C. Fu, J. Am. Chem. Soc., 2008, 130, 12645-12647.
Key Words
ID: J48-Y2008-0560
