One-Pot Synthesis of Diarylalkynes Using Palladium-Catalyzed Sonogashira Reaction and Decarboxylative Coupling of sp Carbon and sp2 Carbon
Jeongju Moon, Miso Jeong, Hyungoog Nam, Jinhun Ju, Joong Ho Moon, Hyun Min Jung and Sunwoo Lee*
*Department of Chemistry, Chonnam National University, 300 Yongbong-dong, Buk-gu, Gwangju, 500-757, Republic of Korea, Email: sunwoochonnam.ac.kr
J. Moon, M. Jeong, H. Nam, J. Ju, J. H. Moon, H. M. Jung, S. Lee, Org. Lett., 2008, 10, 945-948.
DOI: 10.1021/ol703130y (free Supporting Information)
Employing propiolic acid as a difunctional alkyne, and using the consecutive reactions of a Sonogashira coupling and a decarboxylative coupling, unsymmetrically substituted diaryl alkynes were obtained in good yield.
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