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Methoxide Ion Promoted Efficient Synthesis of 1,3-Oxathiolane-2-thiones by Reaction of Oxiranes and Carbon Disulfide

Issa Yavari*, Majid Ghazanfarpour-Darjani, Zinatossadat Hossaini, Maryam Sabbaghan, Nargess Hosseini

*Chemistry Department, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran, Email:

I. Yavari, M. Ghazanfarpour-Darjani, Z. Hossaini, M. Sabbaghan, N. Hosseini, Synlett, 2008, 889-891.

DOI: 10.1055/s-2008-1042927


An efficient reaction of carbon disulfide with oxiranes in the presence of sodium hydride (10 mol%) and methanol gives functionalized 1,3­oxathiolane-2-thiones in very good yields.

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Key Words

oxathiolane, oxiranes, carbon disulfide, methoxide ion, S-heterocycles

ID: J60-Y2008-0900