Axial Coordination of NHC Ligands on Dirhodium(II) Complexes: Generation of a New Family of Catalysts
Alexandre F. Trindade, Pedro M. P. Gois*, Líus F. Veiros, Vânia André, M. Teresa Duarte, Carlos A. M. Afonso, Stephen Caddick and F. Geoffrey N. Cloke
*CQFM and CQE, Departamento de Engenharia Qumica e Biolgica,
Complexo I, Instituto Superior Tcnico, Av. Rovisco Pais 1, 1049-001 Lisboa,
Portugal, Email: pedrogois
ist.utl.pt
A. F. Trindade, P. M. P. Gois, L. F. Veiros, V. André, M. T. Duarte, C. A. M. Afonso, S. Caddick, F. G. N. Cloke, J. Org. Chem., 2008, 73, 4076-4086.
DOI: 10.1021/jo800087n
Abstract
An efficient new methodology for the arylation of aldehydes is disclosed which uses dirhodium(II) catalysts and N-heterocyclic carbene (NHC) ligands. An N-heterocyclic carbene monocomplex of dirhodium(II) acetate was shown to be the most active catalyst and was particularly efficient in the arylation of alkyl aldehydes.
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Key Words
ID: J42-Y2008-1360
