Aminocarbonyl Group Containing Hoveyda-Grubbs-Type Complexes: Synthesis and Activity in Olefin Metathesis Transformations

Diane Rix, Fréderic Caijo, Isabelle Laurent, Fabien Boeda, Hervé Clavier*, Steven P. Nolan* and Marc Mauduit

*School of Chemistry, University of St Andrews, St Andrews KY16 9ST, U.K., Email: hc31st-andrews.ac.uk, sn17st-andrews.ac.uk

D. Rix, F. Caijo, I. Laurent, F. Boeda, H. Clavier, S. P. Nolan, M. Mauduit, J. Org. Chem., 2008, 73, 4225-4228.

DOI: 10.1021/jo800203d

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Abstract

The scope of an aminocarbonyl-substituted Hoveyda-Grubbs catalyst is investigated and shows a good tolerance to various substrates in ring-closing metathesis, enyne metathesis, and cross metathesis. ICP-MS analyses illustrate the good affinity of this catalyst for silica gel, as levels of Ru contamination lower than 6 ppm are detected in the final products.

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Indenylidene Ruthenium Complex Bearing a Sterically Demanding NHC Ligand: An Efficient Catalyst for Olefin Metathesis at Room Temperature

H. Clavier, C. A. Urbino-Blanco, S. P. Nolan, Organometallics, 2009, 28, 2848-2854.

Phosphabicyclononane-Containing Ru Complexes: Efficient Pre-Catalysts for Olefin Metathesis Reactions

F. Boeda, H. Clavier, M. Jordaan, W. H. Meyer, S. P. Nolan, J. Org. Chem., 2008, 73, 259-263.

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Key Words

Ring Closing Metathesis, Enyne Metathesis, N-Heterocycles

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ID: J42-Y2008-1470