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Molybdenum(VI) Dichloride Dioxide Catalyzed Synthesis of β-Keto Esters by C-H Insertion of Ethyl Diazoacetate into Aldehydes

Kandasamy Jeyakumar, Dillip Kumar Chand*

*Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, India, Email:

K. Jeyakumar, D. K. Chand, Synthesis, 2008, 1685-1687.

DOI: 10.1055/s-2008-1067029


Aromatic, aliphatic, and heterocyclic aldehydes are successfully condensed with ethyl diazoacetate in the presence of molybdenum(VI) dichloride dioxide as catalyst to obtain the corresponding β-keto esters in high yields at room temperature.

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proposed mechanism

Key Words

molybdenum, catalyst, β-keto esters, aldehydes, ethyl diazoacetate

ID: J66-Y2008-1500