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Efficient Preparation of Terminal Conjugated Dienes by Coupling of Dienol Phosphates with Grignard Reagents under Iron Catalysis

Gérard Cahiez, Vanessa Habiak and Olivier Gager

*Laboratoire de Synthèse Organique Sélective et de Chimie Organomtallique (SOSCO), UMR 8123 CNRS-UCP-ESCOM, 5, Mail Gay-Lussac, Neuville sur Oise, F-95031 Cergy-Pontoise cedex, France, Email:

G. Cahiez, V. Habiak, O. Gager, Org. Lett., 2008, 10, 2389-2392.

DOI: 10.1021/ol800816f

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An efficient new route by coupling Grignard reagents and dienol phosphates in the presence of Fe(acac)3 allows a stereoselective preparation of terminal conjugated dienes.

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Key Words


ID: J54-Y2008-1550