Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides
Feng Shi, Jesse P. Waldo, Yu Chen and Richard C. Larock*
*Department of Chemistry, Iowa State University, Ames, Iowa 50010, Email: larockiastate.edu
F. Shi, J. P. Waldo, Y. Chen, R. C. Larock, Org. Lett., 2008, 10, 2409-2412.
A [3 + 2] cycloaddition of azides to benzynes affords a rapid and easy entry to a variety of substituted, functionalized benzotriazoles under mild conditions.
see article for more examples
Synthesis of Benzisoxazoles by the [3 + 2] Cycloaddition of in situ Generated Nitrile Oxides and Arynes
A. V. Dubrovskiy, R. C. Larock., 2010, 12, 1180-1183.
Benzotriazoles, Click Chemistry, 1,3-dipolar Cycloaddition