Rh(I)-Catalyzed Reaction of 2-(Chloromethyl)phenylboronic Acids and Alkynes Leading to Indenes
Masaki Miyamoto, Yasuyuki Harada, Mamoru Tobisu and Naoto Chatani*
*Department of Applied Chemistry, Faculty of Engineering,
Osaka University, Suita, Osaka 565-0871, Japan, Email: chatani
chem.eng.osaka-u.ac.jp
M. Miyamoto, Y. Harada, M. Tobisu, N. Chatani, Org. Lett., 2008, 10, 2975-2978.
DOI: 10.1021/ol8006887
Abstract
The reaction of 2-(chloromethyl)phenylboronic acid with alkynes in the presence of a Rh(I) catalyst gave indene derivatives in high yields. The regioselectivity depends on the steric nature of the substituent on the alkynes.
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Key Words
ID: J54-Y2008-1890
