Organic Chemistry Portal

Abstracts

Search:

One-Pot Synthesis of 2-Substituted Indoles from 2-Aminobenzyl Phosphonium Salts. A Formal Total Synthesis of Arcyriacyanin A

George A. Kraus and Haitao Guo

*Department of Chemistry, Iowa State University, Ames, Iowa 50011, Email: gakrausiastate.edu

G. A. Kraus, H. Guo, Org. Lett., 2008, 10, 3061-3063.

DOI: 10.1021/ol801034x (free Supporting Information)



Abstract

The reaction of (2-aminobenzyl) triphenylphosphonium bromide with aromatic aldehydes or α,β-unsaturated aldehydes under microwave-assisted conditions allows the synthesis of 2-substituted indoles in high yields in a one-pot reaction.


see article for more examples



Key Words

Indoles, Microwave Synthesis


ID: J54-Y2008-2010