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Remarkably Fast Acylation of Alcohols with Benzoyl Chloride Promoted by TMEDA

Tomohumi Sano*

*Faculty of Science, Ibaraki University, 2-1-1 Bunkyo, Mito 310-8512, Japan, Email: tormito.ipc.ibaraki.ac.jp

T. Sano, Synthesis, 1999, 1141-1144.

DOI: 10.1055/s-1999-3521


Abstract

A very fast acylation of alcohols with benzoyl chloride in the presence of TMEDA at -78C afforded the corresponding benzoates in excellent yields.

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Key Words

TMEDA, benzoyl chloride, benzoylation, acylation, chemoselectivity


ID: J66-Y1999-740