Mild and Efficient Chemoselective Deprotection of Anomeric O-Methyl Glycosides with Trityl Tetrafluoroborate
Amit Kumar, Venkata Ramana Doddi and Yashwant D. Vankar*
*Department of Chemistry, Indian Institute of Technology
Kanpur 208 016, India, Email: vankar
iitk.ac.in
A. Kumar, V. R. Doddi, Y. D. Vankar, J. Org. Chem., 2008, 73, 5993-5995.
DOI: 10.1021/jo800693w
Abstract
A facile chemoselective deprotection of anomeric O-methyl glycosides affords the corresoponding lactols in very good yields within 10-40 min with use of trityl tetrafluoroborate in dichloromethane at ambient temperatures. The present method is easily implemented and tolerates various functional groups.
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ID: J42-Y2008-2130
