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Efficient Synthesis of Sulfonyl Azides from Sulfonamides

Jessica Raushel, Suresh M. Pitram and Valery V. Fokin

*Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, Email: fokinscripps.edu

J. Raushel, S. M. Pitram, V. V. Fokin, Org. Lett., 2008, 10, 3385-3388.

DOI: 10.1021/ol8011088


Abstract

Triflyl azide serves as an efficient diazo transfer reagent in a direct synthesis of sulfonyl azide building blocks from readily available and stable sulfonamides. The process is experimentally simple, mild, and high-yielding.

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Key Words

Azides


ID: J54-Y2008-2220