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Iodobenzene Dichloride in Combination with Sodium Azide for the Effective Synthesis of Carbamoyl Azides from Aldehydes

Xiao-Qiang Li, Xue-Fei Zhao, Chi Zhang*

*The State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. of China, Email:

X.-Q. Li, X.-F. Zhao, C. Zhang, Synthesis, 2008, 2589-2593.

DOI: 10.1055/s-2008-1067196


Various aliphatic and aromatic aldehydes are converted into their corresponding carbamoyl azides in very good yields in the presence of iodobenzene dichloride and sodium azide in acetonitrile under nitrogen.

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proposed mechanism

Key Words

aldehydes, carbamoyl azides, hypervalent iodine, iodobenzene dichloride, oxidations, Curtius rearrangement

ID: J66-Y2008-2240