Mild and Highly Efficient Method for the Synthesis of 2-Arylbenzimidazoles and 2-Arylbenzothiazoles
Kiumars Bahrami*, M. Mehdi Khodaei* and Fardin Naali
*Department of Chemistry, Razi University, Kermanshah 67149, Iran, Email: kbahrami2hotmail.com, mmkhodarazi.ac.ir
K. Bahrami, M. M. Khodaei, F. Naali, J. Org. Chem., 2008, 73, 6835-6837.
DOI: 10.1021/jo8010232 (free Supporting Information)
A convenient method for the synthesis of 2-substituted benzimidazoles and benzothizoles offers short reaction times, large-scale synthesis, easy and quick isolation of the products, excellent chemoselectivity, and excellent yields as main advantages.
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proposed reaction pathway
K. Bahrami, M. M. Khodaei, I. Kavianinia, Synthesis, 2007, 417-427.