Organic Chemistry Portal



Olefin Ring Closing Metathesis and Hydrosilylation Reaction in Aqueous Medium by Grubbs Second Generation Ruthenium Catalyst

Vivek Polshettiwar and Rajender S. Varma*

*Sustainable Technology Division, National Risk Management Research Laboratory, U.S. Environmental Protection Agency, MS 443, Cincinnati, Ohio 45268, Email:

V. Polshettiwar, R. S. Varma, J. Org. Chem., 2008, 73, 7417-7419.

DOI: 10.1021/jo801330c

see article for more reactions


Grubbs second generation ruthenium catalyst catalyzes various ring closing metathesis and hydrosilylation reactions in aqueous medium. Reactions proceeded in pure water without any additives or cosolvents, in a short period of time. We found that inhomogeneity of the reaction mixture does not prevent high conversion of the products in both reactions.

see article for more examples

Key Words

Ring Closing Metathesis, 3-Pyrrolines, Green Chemistry

ID: J42-Y2008-2620