Palladium-Catalyzed Direct C-2 Arylation of Indoles with Potassium Aryltrifluoroborate Salts
Jinlong Zhao, Yuhong Zhang* and Kai Cheng
*Department of Chemistry, Zhejiang University, Hangzhou 310027, Peoples Republic of China, Email: yhzhangzju.edu.cn
J. Zhao, Y. Zhang, K. Cheng, J. Org. Chem., 2008, 73, 7428-7431.
DOI: 10.1021/jo801371w (free Supporting Information)
A mild, Pd(OAc)2-catalyzed regioselective cross-coupling between indoles and potassium aryltrifluoroarylborates gives 2-aryl indoles in moderate yields in the presence of Cu(OAc)2 in acetic acid at room temperature.
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