[(CyPF-tBu)PdCl2]: An Air-Stable, One-Component, Highly Efficient Catalyst for Amination of Heteroaryl and Aryl Halides
Qilong Shen and John F. Hartwig*
*Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, Email: jhartwiguiuc.edu
Q. Sheng, J. F. Hartwig, Org. Lett., 2008, 10, 4109-4112.
An air- and moisture-stable palladium catalyst, [(CyPF-tBu)PdCl2], for coupling of heteroaryl chlorides, bromides, and iodides with a variety of primary amines is described. Most of these reactions occurred in high yield with 0.001−0.05 mol % catalyst loading. The reactions tolerated a wide range of functional groups.
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Palladium-Catalyzed Coupling of Ammonia with Aryl Chlorides, Bromides, Iodides, and Sulfonates: A General Method for the Preparation of Primary Arylamines
G. D. Vo, J. F. Hartwig, J. Am. Chem. Soc., 2009, 131, 11049-11061.